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Software Engineer, Staff: Applied AI, Science & Engineering

Anthropic

Hybrid — New York City, NY; San Francisco, CA; Seattle, WA · San Francisco, CAListed todayPosted by the employer Oct 6, 2026Listing ends Dec 28, 2026

Compensation: $405k–$485k
Location: New York, NYSan Francisco, CASeattle, WA
HybridMore hybrid jobs: United States
Employment: Full-time
Category: Engineering

Role skills

evaluation simulation ai data pipelines integrations research mechanical engineering machine learning

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About the job

6 min read9 sections

About Anthropic

Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems.

About the role

At Anthropic, we're building AI systems that are safe, beneficial, and transformative. Our mission is to develop AI that benefits humanity, and we believe the most powerful capabilities emerge when we thoughtfully bridge the gap between research breakthroughs and real-world applications.

Claude is getting good at research. Given a well-posed problem, it can read the literature, write and run simulations, analyze results, and iterate on a design across physics, materials, chemistry, and engineering. But most of the hardest problems in science and engineering aren't well-posed. They live inside companies and labs with their own data, tools, constraints, and experts, and progress depends on turning all of that into work a model can actually do and check.

Our Applied AI, Science & Engineering team takes Claude to the scientists and engineers working on hard problems in energy, materials, hardware design, and other physical-world fields. We build the tools Claude needs to do real research and engineering work. Mostly that means software: the agent harnesses, integrations, evaluations, and working processes that turn a partner's problem into something Claude can make progress on and validate. We find real-world problems and test what we build through partner engagements, then feed our learnings back to our research and product teams. It's early, and the engineers who join now will shape how Claude gets applied to science and engineering.

This is an engineering role first. You'll spend real time with domain experts, become the person who knows how to get Claude working in their field, and prototype quickly alongside them. Most of your time, though, goes into building and hardening the systems that make that work repeatable, not into writing recommendations or configuring someone else's product. A science or engineering background is a big plus, but what matters most is that you can earn the trust of expert researchers, turn a fuzzy problem into something concrete and checkable, and ship.

Responsibilities

Build the agent harnesses and research loops that let Claude carry a problem from literature review through hypothesis generation, simulation, analysis, and design iteration
Connect scientific computing and simulation tools (finite element, CFD, electromagnetic, or molecular modeling codes, for example) so Claude can drive them reliably and at scale
Design and build evaluations that tell us whether Claude's work is actually right, and be honest about where it isn't
Sit with scientists and engineers at partner organizations to learn their problem, data, tools, and constraints, and turn open-ended questions into well-specified, verifiable tasks with clear success criteria
Prototype with partners, ship pilots into their workflows, and cut anything that doesn't move the problem forward
Turn what works in one engagement into shared tools, reusable components, and documented processes the next one can start from
Be the technical voice on how Claude performs on science and engineering work, explaining results, limits, and tradeoffs clearly to researchers, engineering leads, and non-technical stakeholders alike
Partner with our research and product teams to share where models fall short on science and engineering work, and help shape what comes next

You may be a good fit if you

Have 8+ years of experience building software, with strong engineering fundamentals and comfort across the stack, from data pipelines to tooling to quick interfaces
Have built real systems with large language models, including agents, tool use, or evaluations
Have worked on technical problems in a science or engineering field, such as physics, materials, chemistry, or electrical or mechanical engineering
Have a track record of zero-to-one work in startup or startup-like environments\
Can work directly with expert users, understand their workflows deeply, and still keep the focus on building the right system rather than the one first requested
Have good judgment about what can and can't be verified, and are comfortable saying a result isn't good enough yet
Bring high agency, pick up new domains quickly, and hold strong opinions loosely
Communicate clearly with researchers, engineers, and external partners, and care about the societal impacts of your work

Strong candidates may also have

An advanced degree or research experience in a physical science or engineering field
Hands-on experience with scientific computing and simulation, numerical methods, or optimization
Experience in industrial R&D, a national lab, or a deep-tech company in areas like energy, materials, manufacturing, or hardware
Experience building alongside customers or technical partners, for example in forward-deployed, applied AI, or solutions engineering roles, ideally where you also owned the software that came out of it
Experience with ML research, RL environments, or evaluation design

Candidates need not have

- 100% of the skills listed above

- Formal certifications or education credentials

- Expertise in every scientific domain we work in

- Direct machine learning or AI research experience

Deadline to apply: None. Applications will be reviewed on a rolling basis. The annual compensation range for this role is listed below.

For sales roles, the range provided is the role’s On Target Earnings ("OTE") range, meaning that the range includes both the sales commissions/sales bonuses target and annual base salary for the role.

Annual Salary

$405,000 — $485,000 USD

Logistics

Minimum education: Bachelor’s degree or an equivalent combination of education, training, and/or experience

Required field of study: A field relevant to the role as demonstrated through coursework, training, or professional experience

Minimum years of experience: Years of experience required will correlate with the internal job level requirements for the position

Location-based hybrid policy: Currently, we expect all staff to be in one of our offices at least 25% of the time. However, some roles may require more time in our offices.

Visa sponsorship: We do sponsor visas! However, we aren't able to successfully sponsor visas for every role and every candidate. But if we make you an offer, we will make every reasonable effort to get you a visa, and we retain an immigration lawyer to help with this.

We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.

Your safety matters to us. To protect yourself from potential scams, remember that Anthropic recruiters only contact you from @anthropic.com email addresses. In some cases, we may partner with vetted recruiting agencies who will identify themselves as working on behalf of Anthropic. Be cautious of emails from other domains. Legitimate Anthropic recruiters will never ask for money, fees, or banking information before your first day. If you're ever unsure about a communication, don't click any links—visit anthropic.com/careers directly for confirmed position openings.

How we're different

We believe that the highest-impact AI research will be big science. At Anthropic we work as a single cohesive team on just a few large-scale research efforts. And we value impact — advancing our long-term goals of steerable, trustworthy AI — rather than work on smaller and more specific puzzles. We view AI research as an empirical science, which has as much in common with physics and biology as with traditional efforts in computer science. We're an extremely collaborative group, and we host frequent research discussions to ensure that we are pursuing the highest-impact work at any given time. As such, we greatly value communication skills.

The easiest way to understand our research directions is to read our recent research. This research continues many of the directions our team worked on prior to Anthropic, including: GPT-3, Circuit-Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences.

Come work with us!

Anthropic is a public benefit corporation headquartered in San Francisco. We offer competitive compensation and benefits, optional equity donation matching, generous vacation and parental leave, flexible working hours, and a lovely office space in which to collaborate with colleagues. Guidance on Candidates' AI Usage: Learn about our policy for using AI in our application process.

Role signals

Market pay: Top quartile for EngineeringCompared with 458 USD annual base ranges in Engineering
Benefits: ,

About Anthropic

Anthropic, PBC is an American artificial intelligence (AI) public benefit corporation headquartered in San Francisco, California. Its flagship product is Claude…Based on Wikipedia · CC BY-SA 4.0